Histidine-Containing Bisperoxovanadium(V) Compounds: Insight Into the Solution Structure by an ESI-MS and51V-NMR Comparative Study

1999 ◽  
Vol 1999 (9) ◽  
pp. 1489-1495 ◽  
Author(s):  
Olga Bortolini ◽  
Mauro Carraro ◽  
Valeria Conte ◽  
Stefano Moro
Keyword(s):  
Comparative Study ◽  
Solution Structure ◽  
Esi Ms ◽  
Insight Into

scholarly journals Insight into the HIV-1 Vif SOCS-box–ElonginBC interaction

Open Biology ◽  
2013 ◽  
Vol 3 (11) ◽  
pp. 130100 ◽  
Author(s):  
Zhisheng Lu ◽  
Julien R. C. Bergeron ◽  
R. Andrew Atkinson ◽  
Torsten Schaller ◽  
Dennis A. Veselkov ◽  
...  
Keyword(s):  
Solution Structure ◽  
Hydrophobic Interactions ◽  
Dynamic Information ◽  
Ubiquitin Ligase Complex ◽  
Biophysical Studies ◽  
Viral Infectivity Factor ◽  
Β Sheet ◽  
Socs Box ◽  
Insight Into ◽  
Hiv 1

The HIV-1 viral infectivity factor (Vif) neutralizes cell-encoded antiviral APOBEC3 proteins by recruiting a cellular ElonginB (EloB)/ElonginC (EloC)/Cullin5-containing ubiquitin ligase complex, resulting in APOBEC3 ubiquitination and proteolysis. The suppressors-of-cytokine-signalling-like domain (SOCS-box) of HIV-1 Vif is essential for E3 ligase engagement, and contains a BC box as well as an unusual proline-rich motif. Here, we report the NMR solution structure of the Vif SOCS–ElonginBC (EloBC) complex. In contrast to SOCS-boxes described in other proteins, the HIV-1 Vif SOCS-box contains only one α-helical domain followed by a β-sheet fold. The SOCS-box of Vif binds primarily to EloC by hydrophobic interactions. The functionally essential proline-rich motif mediates a direct but weak interaction with residues 101–104 of EloB, inducing a conformational change from an unstructured state to a structured state. The structure of the complex and biophysical studies provide detailed insight into the function of Vif's proline-rich motif and reveal novel dynamic information on the Vif–EloBC interaction.

scholarly journals Social Polarisation at the Local Level: A Four-Town Comparative Study on the Challenges of Politicising Inequality in Britain

Sociology ◽  
2020 ◽  
pp. 003803852097559 ◽  
Author(s):  
Insa Koch ◽  
Mark Fransham ◽  
Sarah Cant ◽  
Jill Ebrey ◽  
Luna Glucksberg ◽  
...  
Keyword(s):  
Comparative Study ◽  
Local Level ◽  
Social Groups ◽  
Community Analysis ◽  
Common Features ◽  
Social Polarisation ◽  
The Uk ◽  
Missing Middle ◽  
Insight Into

This article examines how intensifying inequality in the UK plays out at a local level, in order to bring out the varied ways polarisation takes place ‘on the ground’. It brings a community analysis buttressed by quantitative framing to the study of economic, spatial and relational polarisation in four towns in the UK. We distinguish differing dynamics of ‘elite-based’ polarisation (in Oxford and Tunbridge Wells) and ‘poverty-based’ polarisation (in Margate and Oldham). Yet there are also common features. Across the towns, marginalised communities express a sense of local belonging. But tensions between social groups also remain strong and all towns are marked by a weak or ‘squeezed middle’. We argue that the weakness of intermediary institutions, including but not limited to the ‘missing middle’, and capable of bridging gaps between various social groups, provides a major insight into both the obstacles to, and potential solutions for, re-politicising inequality today.

Mechanistic insights into the allylic oxidation of aliphatic compounds by tetraamido iron(v) species: A C–H vs. O–H bond activation

2020 ◽  
Vol 44 (44) ◽  
pp. 19103-19112
Author(s):  
Monika ◽  
Azaj Ansari
Keyword(s):  
Comparative Study ◽  
Bond Activation ◽  
Iron Complex ◽  
Catalytic Reactions ◽  
Allylic Oxidation ◽  
Deep Insight ◽  
Aliphatic Compounds ◽  
High Valent ◽  
Insight Into

This work is based on a deep insight into a comparative study of C–H vs. O–H bond activation of allylic compound by the high valent iron complex. Our theoretical findings can help to design catalysts with better efficiency for catalytic reactions.

Formation of contracts for the international sale of goods under Korean law and the CISG

2017 ◽  
Vol 21 (3) ◽  
pp. 208-223
Author(s):  
Byung Mun Lee
Keyword(s):  
Comparative Study ◽  
Design Methodology ◽  
Case Law ◽  
The Other ◽  
Basic Question ◽  
Content Type ◽  
International Sale Of Goods ◽  
The Comparative Study ◽  
International Sales ◽  
Insight Into

Purpose The purpose of this paper is to describe and analyze the rules on the formation of contracts under Korean law and the Contracts for the International Sale of Goods (CISG) in a comparative way and introduce the relevant proposed rules under the Amendment Draft of the Korean Civil Code (KCC). In addition, it attempts to compare and evaluate them in light of the discipline of comparative law. Design/methodology/approach In order to achieve the purposes of the study, it executes a comparative study of the rules as to the formation of contracts of the CISG, Korean law and the Amendment Draft of the KCC. The basic question for this comparative study is placed on whether a solution from one jurisdiction is more logical than the others and to what extent each jurisdiction has responded to protect the reasonable expectations of the parties in the rules as to the formation of contracts. Findings The comparative study finds that most of the rules under the CISG are quite plausible and logical and they are more or less well reflected in the proposals advanced by the KCC amendment committee. On the other hand, the other rules under the CISG which have brought criticisms in terms of their complexity and inconsistent case law invite us their revision or consistent interpretation. The drawbacks of the CISG have also been well responded in the Amendment Draft of the KCC. Nevertheless, it is quite unfortunate that the Amendment Draft of the KCC still has a rule that regards any purported performance with non-material alteration of the terms of an offer as an acceptance. Originality/value This study may provide legal and practical advice to both the seller and the buyer when they enter into a contract for international sales of goods. In addition, it may render us an insight into newly developed or developing rules in this area and show us how they interact with each other. Furthermore, it may be particularly useful in Korea where there is an ongoing discussion for revision of the KCC.

A comparative study of RFID adoption patterns in retail

2021 ◽  
pp. 1-20
Author(s):  
Narges Kasiri ◽  
G. Scott Erickson ◽  
Gerd Wolfram
Keyword(s):  
Comparative Study ◽  
Radio Frequency ◽  
Radio Frequency Identification ◽  
Structural Model ◽  
Slow Pace ◽  
The Us ◽  
Frequency Identification ◽  
Insight Into ◽  
Current Stage ◽  
Over Time

Radio frequency identification (RFID) has been viewed as a promising technology for quite some time. Initially developed a couple of decades ago, the technology has been accompanied by predictions of imminent widespread adoption since its beginnings. A majority of retailers and other users are now using or planning to use the technology. This paper employs a combination of the technology-organization-environment (TOE) model and the 3-S (substitution, scale, structural) model to analyze the long journey of RFID adoption in retail. Top retail executives in the US and Europe were interviewed to investigate RFID adoption patterns based on differences in technological, organizational, and environmental circumstances. As the retail industry is moving into a post-adoption era, these results demonstrate the current stage of retail RFID adoption, identify factors playing important roles over time as motivators or impediments, and provide some insight into the slow pace of adoption.

A SURVEY ON CLOUD-DENIAL OF SERVICE

2020 ◽  
Vol 1 (2) ◽  
pp. 1-5
Author(s):  
Bibek Naha ◽  
Siddhartha Banerjee ◽  
Sayanti Mondal
Keyword(s):  
Cloud Computing ◽  
Comparative Study ◽  
Denial Of Service ◽  
Distributed Denial Of Service ◽  
Cloud Environment ◽  
Dos Attack ◽  
Huge Amount ◽  
Denial Of Service Attack ◽  
Service Attack ◽  
Insight Into

Cloud Computing is one of the most nurtured as well as debated topic in today’s world. Billions of data of various fields ranging from personal users to large business enterprises reside in Cloud. Therefore, availability of this huge amount of data and services is of immense importance. The DOS (Denial of Service) attack is a well-known threat to the availability of data in a smaller premise. Whenever, it’s a Cloud environment this simple DOS attack takes the form of DDOS (Distributed Denial of Service) attack. This paper provides a generic insight into the various kinds of DOS as well as DDOS attacks. Moreover, a handful of countermeasures have also been depicted here. In a nutshell, it aims at raising an awareness by outlining a clear picture of the Cloud availability issues.Our paper gives a comparative study of different techniques of detecting DOS.

Separation and identification of phenolic compounds in canned artichoke by LC/DAD/ESI-MS using core–shell C18 column: A comparative study

2013 ◽  
Vol 927 ◽  
pp. 173-180 ◽  
Author(s):  
Jianbing Wu ◽  
Yongsheng Qian ◽  
Peipei Mao ◽  
Linyao Chen ◽  
Yanbin Lu ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Comparative Study ◽  
Core Shell ◽  
Esi Ms

Designing the Person: Sociological Assumptions Embodied within the Architecture of Charles Rennie Mackintosh and Le Corbusier

2005 ◽  
Vol 14 (1) ◽  
pp. 141-162
Author(s):  
Clare Spencer
Keyword(s):  
Social Interaction ◽  
Comparative Study ◽  
Le Corbusier ◽  
Western Society ◽  
Architectural Practice ◽  
Individual Person ◽  
Interesting Insight ◽  
Starting Point ◽  
The Individual ◽  
Insight Into

This essay presents a comparative study of the sociological assumptions implicit, and to some extent explicit, in the work of two famous architects, Charles Rennie Mackintosh and Le Corbusier. The inhabitant implied through the architectural practice of Le Corbusier resembles Elias's homo clausus (closed person), the mode of self experience viewed by Elias as the dominant one in Western society and one which sees the individual person as a ‘thinking subject’ and the starting point of knowledge. Mackintosh's designs, in contrast, imply individual people closer to Elias‘s homines aperti, social beings who are shaped through social interaction and interdependence. This paper demonstrates how, as well as fulfilling social, cultural and political needs, architecture carries, within in its designs, certain assumptions about how people and how they do, and should, live. The adoption of an Eliasian perspective provides an interesting insight into how these assumptions can shape self-experience and social interaction in the buildings of each architect.

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